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Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry
Herpes simplex virus (HSV) is an important human pathogen. It enters cells through an orchestrated process that requires four essential glycoproteins, gD, gH/gL, and gB, activated in cascade fashion by receptor-binding and signaling. gH/gL heterodimer is conserved across the Herpesviridae family. HS...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517248/ https://ncbi.nlm.nih.gov/pubmed/26157134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506846112 |
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