Stereodivergent Organocatalytic Intramolecular Michael Addition/Lactonization for the Asymmetric Synthesis of Substituted Dihydrobenzofurans and Tetrahydrofurans

A stereodivergent asymmetric Lewis base catalyzed Michael addition/lactonization of enone acids into substituted dihydrobenzofuran and tetrahydrofuran derivatives is reported. Commercially available (S)-(−)-tetramisole hydrochloride gives products with high syn diastereoselectivity in excellent enan...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Belmessieri, Dorine, de la Houpliere, Alix, Calder, Ewen D D, Taylor, James E, Smith, Andrew D
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2014
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517160/
https://ncbi.nlm.nih.gov/pubmed/24989672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201402684
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