Citrulline Supplementation Improves Organ Perfusion and Arginine Availability under Conditions with Enhanced Arginase Activity

Enhanced arginase-induced arginine consumption is believed to play a key role in the pathogenesis of sickle cell disease-induced end organ failure. Enhancement of arginine availability with l-arginine supplementation exhibited less consistent results; however, l-citrulline, the precursor of l-argini...

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Vydáno v:Nutrients
Hlavní autoři: Wijnands, Karolina A.P., Meesters, Dennis M., van Barneveld, Kevin W.Y., Visschers, Ruben G.J., Briedé, Jacob J., Vandendriessche, Benjamin, van Eijk, Hans M.H., Bessems, Babs A.F.M., van den Hoven, Nadine, von Wintersdorff, Christian J.H., Brouckaert, Peter, Bouvy, Nicole D., Lamers, Wouter H., Cauwels, Anje, Poeze, Martijn
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516994/
https://ncbi.nlm.nih.gov/pubmed/26132994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu7075217
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