Citrulline Supplementation Improves Organ Perfusion and Arginine Availability under Conditions with Enhanced Arginase Activity

Enhanced arginase-induced arginine consumption is believed to play a key role in the pathogenesis of sickle cell disease-induced end organ failure. Enhancement of arginine availability with l-arginine supplementation exhibited less consistent results; however, l-citrulline, the precursor of l-argini...

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Veröffentlicht in:Nutrients
Hauptverfasser: Wijnands, Karolina A.P., Meesters, Dennis M., van Barneveld, Kevin W.Y., Visschers, Ruben G.J., Briedé, Jacob J., Vandendriessche, Benjamin, van Eijk, Hans M.H., Bessems, Babs A.F.M., van den Hoven, Nadine, von Wintersdorff, Christian J.H., Brouckaert, Peter, Bouvy, Nicole D., Lamers, Wouter H., Cauwels, Anje, Poeze, Martijn
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516994/
https://ncbi.nlm.nih.gov/pubmed/26132994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu7075217
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