Citrulline a More Suitable Substrate than Arginine to Restore NO Production and the Microcirculation during Endotoxemia

BACKGROUND: Impaired microcirculation during endotoxemia correlates with a disturbed arginine-nitric oxide (NO) metabolism and is associated with deteriorating organ function. Improving the organ perfusion in endotoxemia, as often seen in patients with severe infection or systemic inflammatory respo...

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Main Authors: Wijnands, Karolina A. P., Vink, Hans, Briedé, Jacob J., van Faassen, Ernst E., Lamers, Wouter H., Buurman, Wim A., Poeze, Martijn
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362574/
https://ncbi.nlm.nih.gov/pubmed/22666356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037439
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