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Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula
Voltage-gated sodium (Na(V)) channels are responsible for propagating action potentials in excitable cells. Na(V)1.7 plays a crucial role in the human pain signalling pathway and it is an important therapeutic target for treatment of chronic pain. Numerous spider venom peptides have been shown to mo...
Guardat en:
| Publicat a: | Toxins (Basel) |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516925/ https://ncbi.nlm.nih.gov/pubmed/26134258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7072494 |
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