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Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula
Voltage-gated sodium (Na(V)) channels are responsible for propagating action potentials in excitable cells. Na(V)1.7 plays a crucial role in the human pain signalling pathway and it is an important therapeutic target for treatment of chronic pain. Numerous spider venom peptides have been shown to mo...
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| Publicado no: | Toxins (Basel) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516925/ https://ncbi.nlm.nih.gov/pubmed/26134258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7072494 |
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