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A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc

N-methyl-d-aspartate (NMDA) receptors, one of the three main types of ionotropic glutamate receptors (iGluRs), are involved in excitatory synaptic transmission, and their dysfunction is implicated in various neurological disorders. NMDA receptors, heterotetramers typically composed of GluN1 and GluN...

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Publicado en:J Gen Physiol
Autores principales: Sirrieh, Rita E., MacLean, David M., Jayaraman, Vasanthi
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516779/
https://ncbi.nlm.nih.gov/pubmed/26170175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511422
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