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STriatal-Enriched protein tyrosine Phosphatase (STEP) Regulates the PTPα/Fyn Signaling Pathway

The tyrosine kinase Fyn has two regulatory tyrosine residues that when phosphorylated either activate (Tyr(420)) or inhibit (Tyr(531)) Fyn activity. Within the central nervous system, two protein tyrosine phosphatases (PTPs) target these regulatory tyrosines in Fyn. PTPα dephosphorylates Tyr(531) an...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Xu, Jian, Kurup, Pradeep, Foscue, Ethan, Lombroso, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516628/
https://ncbi.nlm.nih.gov/pubmed/25951993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13160
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