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STriatal-Enriched protein tyrosine Phosphatase (STEP) Regulates the PTPα/Fyn Signaling Pathway

The tyrosine kinase Fyn has two regulatory tyrosine residues that when phosphorylated either activate (Tyr(420)) or inhibit (Tyr(531)) Fyn activity. Within the central nervous system, two protein tyrosine phosphatases (PTPs) target these regulatory tyrosines in Fyn. PTPα dephosphorylates Tyr(531) an...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Xu, Jian, Kurup, Pradeep, Foscue, Ethan, Lombroso, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516628/
https://ncbi.nlm.nih.gov/pubmed/25951993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13160
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