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Single-Cell Analysis of Mast Cell Degranulation Induced by Airway Smooth Muscle-Secreted Chemokines

BACKGROUND: Asthma is a chronic inflammatory disease characterized by narrowed airways, bronchial hyper-responsiveness, mucus hyper-secretion, and airway remodeling. Mast cell (MC) infiltration into airway smooth muscle (ASM) is a defining feature of asthma, and ASM regulates the inflammatory respon...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Manning, Benjamin M., Meyer, Audrey F., Gruba, Sarah M., Haynes, Christy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516622/
https://ncbi.nlm.nih.gov/pubmed/25986989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2015.05.008
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