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T-bet is induced by interferon-γ to mediate chemokine secretion and migration in human airway smooth muscle cells
An inappropriate balance between T-helper (Th)1 and Th2 cytokine production underlies inflammatory changes that result in airway disease. Expression of the T-box transcription factor T-bet regulates differentiation of Th cells and production of Th1 cytokines, particularly IFNγ. T-bet-deficient mice...
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| 主要作者: | |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075099/ https://ncbi.nlm.nih.gov/pubmed/21239533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00163.2010 |
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