Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response

Taxane and vinblastine represent two classes of microtubules-targeted agents for cancer chemotherapy. Although taxol and vinblastine are widely used for cancer treatment, resistance to these agents is frequently encountered in the clinic. An ongoing question has been what mechanisms are involved in...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Wang, Jiao, Yin, Yancun, Hua, Hui, Li, Minjing, Luo, Ting, Xu, Li, Wang, Ranran, Liu, Dongbo, Zhang, You, Jiang, Yangfu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2009
Témata:
Molecular Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516536/
https://ncbi.nlm.nih.gov/pubmed/19674193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00873.x
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