Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response

Taxane and vinblastine represent two classes of microtubules-targeted agents for cancer chemotherapy. Although taxol and vinblastine are widely used for cancer treatment, resistance to these agents is frequently encountered in the clinic. An ongoing question has been what mechanisms are involved in...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Wang, Jiao, Yin, Yancun, Hua, Hui, Li, Minjing, Luo, Ting, Xu, Li, Wang, Ranran, Liu, Dongbo, Zhang, You, Jiang, Yangfu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2009
Assuntos:
Molecular Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516536/
https://ncbi.nlm.nih.gov/pubmed/19674193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00873.x
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