Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response

Taxane and vinblastine represent two classes of microtubules-targeted agents for cancer chemotherapy. Although taxol and vinblastine are widely used for cancer treatment, resistance to these agents is frequently encountered in the clinic. An ongoing question has been what mechanisms are involved in...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Wang, Jiao, Yin, Yancun, Hua, Hui, Li, Minjing, Luo, Ting, Xu, Li, Wang, Ranran, Liu, Dongbo, Zhang, You, Jiang, Yangfu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2009
Fag:
Molecular Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516536/
https://ncbi.nlm.nih.gov/pubmed/19674193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00873.x
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