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Functional characterization and pharmacological rescue of melanocortin-4 receptor mutations identified from obese patients

As the most common monogenic form of human obesity, about 130 naturally occurring melanocortin-4 receptor (MC4R) gene mutations have been identified. In this study, we reported detailed functional characterization of 10 novel human MC4R (hMC4R) mutants including R7C, C84R, S127L, S136F, W174C, A219V...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Fan, Zhen-Chuan, Tao, Ya-Xiong
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516484/
https://ncbi.nlm.nih.gov/pubmed/19298524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00726.x
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