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Mechanisms underlying fibronectin-induced up-regulation of P2X(4)R expression in microglia: distinct roles of PI3K–Akt and MEK–ERK signalling pathways
ABSTRACT: MICROGLIA: are resident immune cells in the central nervous system that become activated and produce pro-inflammatory and neurotrophic factors upon activation of various cell-surface receptors. The P2X(4) receptor (P2X(4)R) is a sub-type of the purinergic ion-channel receptors expressed in...
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516482/ https://ncbi.nlm.nih.gov/pubmed/19298529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00719.x |
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