Intrathecal delivery of PDGF produces tactile allodynia through its receptors in spinal microglia

Neuropathic pain is a debilitating pain condition that occurs after nerve damage. Such pain is considered to be a reflection of the aberrant excitability of dorsal horn neurons. Emerging lines of evidence indicate that spinal microglia play a crucial role in neuronal excitability and the pathogenesi...

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Bibliographic Details
Main Authors: Masuda, Junya, Tsuda, Makoto, Tozaki-Saitoh, Hidetoshi, Inoue, Kazuhide
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690582/
https://ncbi.nlm.nih.gov/pubmed/19426564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-5-23
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