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IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype
Microglia become activated by multiple types of damage in the nervous system and play essential roles in neuronal pathologies. However, how micro-glia transform into reactive phenotypes is poorly understood. Here, we identify the transcription factor interferon regulatory factor 8 (IRF8) as a critic...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158926/ https://ncbi.nlm.nih.gov/pubmed/22832225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.02.014 |
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