TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms

Terminal uridylyl transferases (TUTs) function as integral regulators of microRNA (miRNA) biogenesis. Using biochemistry, single-molecule, and deep sequencing techniques, we here investigate the mechanism by which human TUT7 (also known as ZCCHC6) recognizes and uridylates precursor miRNAs (pre-miRN...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Kim, Boseon, Ha, Minju, Loeff, Luuk, Chang, Hyeshik, Simanshu, Dhirendra K, Li, Sisi, Fareh, Mohamed, Patel, Dinshaw J, Joo, Chirlmin, Kim, V Narry
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516432/
https://ncbi.nlm.nih.gov/pubmed/25979828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201590931
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