Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4)

Recent small RNA sequencing data has uncovered 3′ end modification of mature microRNAs (miRNAs). This non-templated nucleotide addition can impact miRNA gene regulatory networks through the control of miRNA stability or by interfering with the repression of target mRNAs. The miRNA modifying enzymes...

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Bibliographic Details
Main Authors: Thornton, James E., Du, Peng, Jing, Lili, Sjekloca, Ljiljana, Lin, Shuibin, Grossi, Elena, Sliz, Piotr, Zon, Leonard I., Gregory, Richard I.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191393/
https://ncbi.nlm.nih.gov/pubmed/25223788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku805
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