Influence of kynurenine 3-monooxygenase (KMO) gene polymorphism on cognitive function in schizophrenia,

BACKGROUND: Cognitive deficits compromise quality of life and productivity for individuals with schizophrenia and have no effective treatments. Preclinical data point to the kynurenine pathway of tryptophan metabolism as a potential target for pro-cognitive drug development. We have previously demon...

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Pubblicato in:Schizophr Res
Autori principali: Wonodi, Ikwunga, McMahon, Robert P., Krishna, Nithin, Mitchell, Braxton D., Liu, Judy, Glassman, Matthew, Hong, L. Elliot, Gold, James M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516229/
https://ncbi.nlm.nih.gov/pubmed/25464917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2014.10.026
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