Downregulated Kynurenine 3-Monooxygenase Gene Expression and Enzyme Activity in Schizophrenia and Genetic Association With Schizophrenia Endophenotypes

CONTEXT: Kynurenic acid, a metabolite of the kynurenine pathway of tryptophan degradation, is an antagonist at N-methyl-d-aspartate and α7 nicotinic acetylcholine receptors and modulates glutamate, dopamine, and acetylcholine signaling. Cortical kynurenic acid concentrations are elevated in the brai...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wonodi, Ikwunga, Stine, O. Colin, Sathyasaikumar, Korrapati V., Roberts, Rosalinda C., Mitchell, Braxton D., Hong, L. Elliot, Kajii, Yasushi, Thaker, Gunvant K., Schwarcz, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855543/
https://ncbi.nlm.nih.gov/pubmed/21727251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2011.71
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados