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Cortical Kynurenine Pathway Metabolism: A Novel Target for Cognitive Enhancement in Schizophrenia

The brain concentration of kynurenic acid (KYNA), a metabolite of the kynurenine pathway of tryptophan degradation and antagonist at both the glycine coagonist site of the N-methyl-D-aspartic acid receptor (NMDAR) and the α7 nicotinic acetylcholine receptor (α7nAChR), is elevated in the prefrontal c...

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Detaylı Bibliyografya
Asıl Yazarlar: Wonodi, Ikwunga, Schwarcz, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833131/
https://ncbi.nlm.nih.gov/pubmed/20147364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbq002
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