Insulin-induced activation of glycerol-3-phosphate acyltransferase by a chiro-inositol-containing insulin mediator is defective in adipocytes of insulin-resistant, type II diabetic, Goto-Kakizaki rats.

Type II diabetic Goto-Kakizaki (GK) rats were insulin-resistant in euglycemic-hyperinsulinemic clamp studies. We therefore examined insulin signaling systems in control Wistar and diabetic GK rats. Glycerol-3-phosphate acyltransferase (G3PAT), which is activated by headgroup mediators released from...

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Detalhes bibliográficos
Main Authors: Farese, R V, Standaert, M L, Yamada, K, Huang, L C, Zhang, C, Cooper, D R, Wang, Z, Yang, Y, Suzuki, S, Toyota, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC45162/
https://ncbi.nlm.nih.gov/pubmed/7972005
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