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Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids

The role of autophagy in cell death is still controversial and a lot of debate has concerned the transition from its pro-survival to its pro-death roles. The similar structure of the triterpenoids Betulinic (BA) and Oleanolic (OA) acids allowed us to prove that this transition involves parallel dama...

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Publicat a:Sci Rep
Autors principals: Martins, Waleska K., Costa, Érico T., Cruz, Mário C., Stolf, Beatriz S., Miotto, Ronei, Cordeiro, Rodrigo M., Baptista, Maurício S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515638/
https://ncbi.nlm.nih.gov/pubmed/26213355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12425
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