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Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity

The extracellular sulfatases Sulf1 and Sulf2 remove specific 6-O-sulfate groups from heparan sulfate, thereby modulating numerous signalling pathways underlying development and homeostasis. In vitro data have suggested that the two enzymes show functional redundancy. To elucidate their in vivo funct...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Kalus, Ina, Salmen, Benedikt, Viebahn, Christoph, von Figura, Kurt, Schmitz, Dietmar, D'Hooge, Rudi, Dierks, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515066/
https://ncbi.nlm.nih.gov/pubmed/20394677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00558.x
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