Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity

HS (heparan sulfate) is essential for normal embryonic development. This requirement is due to the obligatory role for HS in the signalling pathways of many growth factors and morphogens that bind to sulfated domains in the HS polymer chain. The sulfation patterning of HS is determined by a complex...

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Detalhes bibliográficos
Main Authors: Lamanna, William C., Baldwin, Rebecca J., Padva, Michael, Kalus, Ina, ten Dam, Gerdy, van Kuppevelt, Toin H., Gallagher, John T., von Figura, Kurt, Dierks, Thomas, Merry, Catherine L. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635445/
https://ncbi.nlm.nih.gov/pubmed/16901266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060848
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