CD4+ T cells in aged or thymectomized recipients of allogeneic stem cell transplantations

BACKGROUND: CD4+CD25highFOXP3+ regulatory T (Treg) cells, which include thymus-derived and peripherally induced cells, play a central role in immune regulation, and are therefore crucial to prevent graft-versus-host disease (GVHD). The increasing use of allogeneic hematopoietic stem cell transplanta...

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Bibliografiske detaljer
Udgivet i:Biol Res
Main Authors: Takahashi, Hiroshi, Ikeda, Kazuhiko, Ogawa, Kazuei, Saito, Syunnichi, Ngoma, Alain M, Mashimo, Yumiko, Ueda, Koki, Furukawa, Miki, Shichishima-Nakamura, Akiko, Ohkawara, Hiroshi, Nollet, Kenneth E, Ohto, Hitoshi, Takeishi, Yasuchika
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514962/
https://ncbi.nlm.nih.gov/pubmed/26210500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-015-0033-8
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