The Amelioration of Myelofibrosis with Thrombocytopenia by a JAK1/2 Inhibitor, Ruxolitinib, in a Post-polycythemia Vera Myelofibrosis Patient with a JAK2 Exon 12 Mutation

Less than 5% of patients with polycythemia vera (PV) show JAK2 exon 12 mutations. Although PV patients with JAK2 exon 12 mutations are known to develop post-PV myelofibrosis (MF) as well as PV with JAK2V617F, the role of JAK inhibitors in post-PV MF patients with JAK2 exon 12 mutations remains unkno...

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Detalhes bibliográficos
Publicado no:Intern Med
Main Authors: Ikeda, Kazuhiko, Ueda, Koki, Sano, Takahiro, Ogawa, Kazuei, Ikezoe, Takayuki, Hashimoto, Yuko, Morishita, Soji, Komatsu, Norio, Ohto, Hitoshi, Takeishi, Yasuchika
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Internal Medicine 2017
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519475/
https://ncbi.nlm.nih.gov/pubmed/28674362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.56.7871
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