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Acetate: friend or foe? Efficient production of a sweet protein in Escherichia coli BL21 using acetate as a carbon source
BACKGROUND: Escherichia coli is, to date, the most used microorganism for the production of recombinant proteins and biotechnologically relevant metabolites. High density cell cultures allow efficient biomass and protein yields. However, their main limitation is the accumulation of acetate as a by-p...
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| Publicado no: | Microb Cell Fact |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4514960/ https://ncbi.nlm.nih.gov/pubmed/26208726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0299-0 |
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