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N-Terminal Coiled-Coil Structure of ATPase Subunits of 26S Proteasome Is Crucial for Proteasome Function

The proteasome is an essential proteolytic machine in eukaryotic cells, where it removes damaged proteins and regulates many cellular activities by degrading ubiquitinated proteins. Its heterohexameric AAA+ ATPase Rpt subunits play a central role in proteasome activity by the engagement of substrate...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Inobe, Tomonao, Genmei, Reiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514846/
https://ncbi.nlm.nih.gov/pubmed/26208326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134056
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