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N-Terminal Coiled-Coil Structure of ATPase Subunits of 26S Proteasome Is Crucial for Proteasome Function

The proteasome is an essential proteolytic machine in eukaryotic cells, where it removes damaged proteins and regulates many cellular activities by degrading ubiquitinated proteins. Its heterohexameric AAA+ ATPase Rpt subunits play a central role in proteasome activity by the engagement of substrate...

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Publicado en:PLoS One
Autores principales: Inobe, Tomonao, Genmei, Reiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514846/
https://ncbi.nlm.nih.gov/pubmed/26208326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134056
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