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Fully Flexible Docking of Medium Sized Ligand Libraries with RosettaLigand

RosettaLigand has been successfully used to predict binding poses in protein-small molecule complexes. However, the RosettaLigand docking protocol is comparatively slow in identifying an initial starting pose for the small molecule (ligand) making it unfeasible for use in virtual High Throughput Scr...

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Vydáno v:PLoS One
Hlavní autoři: DeLuca, Samuel, Khar, Karen, Meiler, Jens
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514752/
https://ncbi.nlm.nih.gov/pubmed/26207742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132508
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