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Fully Flexible Docking of Medium Sized Ligand Libraries with RosettaLigand

RosettaLigand has been successfully used to predict binding poses in protein-small molecule complexes. However, the RosettaLigand docking protocol is comparatively slow in identifying an initial starting pose for the small molecule (ligand) making it unfeasible for use in virtual High Throughput Scr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: DeLuca, Samuel, Khar, Karen, Meiler, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514752/
https://ncbi.nlm.nih.gov/pubmed/26207742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132508
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