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Fully Flexible Docking of Medium Sized Ligand Libraries with RosettaLigand

RosettaLigand has been successfully used to predict binding poses in protein-small molecule complexes. However, the RosettaLigand docking protocol is comparatively slow in identifying an initial starting pose for the small molecule (ligand) making it unfeasible for use in virtual High Throughput Scr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: DeLuca, Samuel, Khar, Karen, Meiler, Jens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514752/
https://ncbi.nlm.nih.gov/pubmed/26207742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132508
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