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Novel Apo E-Derived ABCA1 Agonist Peptide (CS-6253) Promotes Reverse Cholesterol Transport and Induces Formation of preβ-1 HDL In Vitro

Apolipoprotein (apo) mimetic peptides replicate some aspects of HDL function. We have previously reported the effects of compound ATI-5261 on its ability to replicate many functions of native apo A-I in the process of HDL biogenesis. ATI-5261 induced muscle toxicity in wild type C57Bl/6 mice, increa...

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Publicat a:PLoS One
Autors principals: Hafiane, Anouar, Bielicki, John K., Johansson, Jan O., Genest, Jacques
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514675/
https://ncbi.nlm.nih.gov/pubmed/26207756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131997
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