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Chlamydia trachomatis In Vivo to In Vitro Transition Reveals Mechanisms of Phase Variation and Down-Regulation of Virulence Factors

Research on the obligate intracellular bacterium Chlamydia trachomatis demands culture in cell-lines, but the adaptive process behind the in vivo to in vitro transition is not understood. We assessed the genomic and transcriptomic dynamics underlying C. trachomatis in vitro adaptation of strains rep...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Borges, Vítor, Pinheiro, Miguel, Antelo, Minia, Sampaio, Daniel A., Vieira, Luís, Ferreira, Rita, Nunes, Alexandra, Almeida, Filipe, Mota, Luís J., Borrego, Maria J., Gomes, João P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514472/
https://ncbi.nlm.nih.gov/pubmed/26207372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133420
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