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Characterization of a recombinant humanized anti-cocaine monoclonal antibody and its Fab fragment

Variations of post-translational modifications are important for stability and in vivo behavior of therapeutic antibodies. A recombinant humanized anti-cocaine monoclonal antibody (h2E2) was characterized for heterogeneity of N-linked glycosylation and disulfide bonds. In addition, charge heterogene...

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書目詳細資料
發表在:Hum Vaccin Immunother
Main Authors: Kirley, Terence L, Norman, Andrew B
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514192/
https://ncbi.nlm.nih.gov/pubmed/25692880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21645515.2014.990856
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