Development of a heat-stable and orally delivered recombinant M2e-expressing B. subtilis spore-based influenza vaccine

Highly conserved ectodomain of influenza virus M2 protein (M2e) is an important target for the development of universal influenza vaccines. Today, the use of chemical or genetic fusion constructs have been undertaken to overcome the low immunogenicity of M2e in vaccine formulation. However, current...

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Bibliografiske detaljer
Udgivet i:Hum Vaccin Immunother
Main Authors: Zhao, Guangyu, Miao, Yu, Guo, Yan, Qiu, Hongjie, Sun, Shihui, Kou, Zhihua, Yu, Hong, Li, Junfeng, Chen, Yue, Jiang, Shibo, Du, Lanying, Zhou, Yusen
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
INFLUENZA/Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514050/
https://ncbi.nlm.nih.gov/pubmed/25483702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.36122
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