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A cis-encoded sRNA, Hfq and mRNA secondary structure act independently to suppress IS200 transposition

IS200 is found throughout Enterobacteriaceae and transposes at a notoriously low frequency. In addition to the transposase protein (TnpA), IS200 encodes an uncharacterized Hfq-binding sRNA that is encoded opposite to the tnpA 5'UTR. In the current work we asked if this sRNA represses tnpA expre...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Ellis, Michael J., Trussler, Ryan S., Haniford, David B.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513863/
https://ncbi.nlm.nih.gov/pubmed/26044710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv584
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