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Controlling tetramer formation, subunit rotation and DNA ligation during Hin-catalyzed DNA inversion

Two critical steps controlling serine recombinase activity are the remodeling of dimers into the chemically active synaptic tetramer and the regulation of subunit rotation during DNA exchange. We identify a set of hydrophobic residues within the oligomerization helix that controls these steps by the...

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Publicat a:Nucleic Acids Res
Autors principals: Chang, Yong, Johnson, Reid C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513852/
https://ncbi.nlm.nih.gov/pubmed/26056171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv565
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