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Controlling tetramer formation, subunit rotation and DNA ligation during Hin-catalyzed DNA inversion

Two critical steps controlling serine recombinase activity are the remodeling of dimers into the chemically active synaptic tetramer and the regulation of subunit rotation during DNA exchange. We identify a set of hydrophobic residues within the oligomerization helix that controls these steps by the...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Chang, Yong, Johnson, Reid C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513852/
https://ncbi.nlm.nih.gov/pubmed/26056171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv565
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