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Controlling tetramer formation, subunit rotation and DNA ligation during Hin-catalyzed DNA inversion

Two critical steps controlling serine recombinase activity are the remodeling of dimers into the chemically active synaptic tetramer and the regulation of subunit rotation during DNA exchange. We identify a set of hydrophobic residues within the oligomerization helix that controls these steps by the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chang, Yong, Johnson, Reid C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513852/
https://ncbi.nlm.nih.gov/pubmed/26056171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv565
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