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Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase
DNA strand exchange by serine recombinases has been proposed to occur by a large-scale rotation of halves of the recombinase tetramer. Here we provide the first direct physical evidence for the subunit rotation mechanism for the Hin serine invertase. Single-DNA looping assays using an activated muta...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817059/ https://ncbi.nlm.nih.gov/pubmed/27032966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23697 |
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