Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase

DNA strand exchange by serine recombinases has been proposed to occur by a large-scale rotation of halves of the recombinase tetramer. Here we provide the first direct physical evidence for the subunit rotation mechanism for the Hin serine invertase. Single-DNA looping assays using an activated muta...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Xiao, Botao, McLean, Meghan M., Lei, Xianbin, Marko, John F., Johnson, Reid C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817059/
https://ncbi.nlm.nih.gov/pubmed/27032966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23697
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