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Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase
Structural and topological data suggest that serine site-specific DNA recombinases exchange duplex DNAs by rigid-body relative rotation of the two halves of the synapse, mediated by a flat protein-protein interaction surface. We present evidence for this rotational motion for a simple serine recombi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088605/ https://ncbi.nlm.nih.gov/pubmed/21502527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018436108 |
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