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Remote control of DNA-acting enzymes by varying the Brownian dynamics of a distant DNA end

Enzyme rates are usually considered to be dependent on local properties of the molecules involved in reactions. However, for large molecules, distant constraints might affect reaction rates by affecting dynamics leading to transition states. In single-molecule experiments we have found that enzymes...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bai, Hua, Kath, James E., Zörgiebel, Felix Manuel, Sun, Mingxuan, Ghosh, Pallavi, Hatfull, Graham F., Grindley, Nigel D. F., Marko, John F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478594/
https://ncbi.nlm.nih.gov/pubmed/23011800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203118109
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