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Unfolding Kinetics of the Human Telomere i-Motif Under a 10 pN Force Imposed by the α-Hemolysin Nanopore Identify Transient Folded-State Lifetimes at Physiological pH
[Image: see text] Cytosine (C)-rich DNA can adopt i-motif folds under acidic conditions, with the human telomere i-motif providing a well-studied example. The dimensions of this i-motif are appropriate for capture in the nanocavity of the α-hemolysin (α-HL) protein pore under an electrophoretic forc...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2015
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513840/ https://ncbi.nlm.nih.gov/pubmed/26110559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03912 |
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