A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirements.

The osteocalcin (OC) silencer is a unique example of exonic sequences contributing to negative transcriptional control of mammalian gene expression. In this paper we demonstrate, using a reporter transfection assay, that multiple elements reside within the OC +24/+151 domain. Thirty-fold repression...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Frenkel, B, Montecino, M, Stein, J L, Lian, J B, Stein, G S
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC45138/
https://ncbi.nlm.nih.gov/pubmed/7971985
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires