Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression

INTRODUCTION: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons as well as the presence of proteinaceous inclusions named Lewy bodies. α-synuclein (α-syn) is a major constituent of Lewy bodies, and the first disease-causing protein...

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Publicado en:Acta Neuropathol Commun
Autores principales: Bourdenx, Mathieu, Dovero, Sandra, Engeln, Michel, Bido, Simone, Bastide, Matthieu F., Dutheil, Nathalie, Vollenweider, Isabel, Baud, Laetitia, Piron, Camille, Grouthier, Virginie, Boraud, Thomas, Porras, Grégory, Li, Qin, Baekelandt, Veerle, Scheller, Dieter, Michel, Anne, Fernagut, Pierre-Olivier, Georges, François, Courtine, Grégoire, Bezard, Erwan, Dehay, Benjamin
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513748/
https://ncbi.nlm.nih.gov/pubmed/26205255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0222-2
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