Tasting Pseudomonas aeruginosa Biofilms: Human Neutrophils Express the Bitter Receptor T2R38 as Sensor for the Quorum Sensing Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone

Bacteria communicate with one another via specialized signaling molecules, known as quorum sensing molecules or autoinducers. The Pseudomonas aeruginosa-derived quorum sensing molecule N-(3-oxododecanoyl)-l-homoserine lactone (AHL-12), however, also activates mammalian cells. As shown previously, AH...

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Pubblicato in:Front Immunol
Autori principali: Maurer, Susanne, Wabnitz, Guido H., Kahle, Nadine A., Stegmaier, Sabine, Prior, Birgit, Giese, Thomas, Gaida, Matthias Martin, Samstag, Yvonne, Hänsch, Gertrud Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513437/
https://ncbi.nlm.nih.gov/pubmed/26257736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00369
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