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Expression of the bitter receptor T2R38 in pancreatic cancer: localization in lipid droplets and activation by a bacteria-derived quorum-sensing molecule

T2R38 belongs to the family of bitter receptors and was initially detected in cells of the oral cavity. We now describe expression of T2R38 in tumor cells in patients with pancreatic cancer and in tumor-derived cell lines. T2R38 is localized predominantly intracellular in association with lipid drop...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Gaida, Matthias M., Mayer, Christine, Dapunt, Ulrike, Stegmaier, Sabine, Schirmacher, Peter, Wabnitz, Guido H., Hänsch, G. Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914309/
https://ncbi.nlm.nih.gov/pubmed/26862855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7206
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