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Expression of the bitter receptor T2R38 in pancreatic cancer: localization in lipid droplets and activation by a bacteria-derived quorum-sensing molecule

T2R38 belongs to the family of bitter receptors and was initially detected in cells of the oral cavity. We now describe expression of T2R38 in tumor cells in patients with pancreatic cancer and in tumor-derived cell lines. T2R38 is localized predominantly intracellular in association with lipid drop...

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發表在:Oncotarget
Main Authors: Gaida, Matthias M., Mayer, Christine, Dapunt, Ulrike, Stegmaier, Sabine, Schirmacher, Peter, Wabnitz, Guido H., Hänsch, G. Maria
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914309/
https://ncbi.nlm.nih.gov/pubmed/26862855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7206
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