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Borane-protected phosphines are redox-active radioprotective agents for endothelial cells

Exposure to radiation can damage endothelial cells in the irradiated area via the production of reactive oxygen species. We synthesized phosphine–borane complexes that reduce disulfide bonds and had previously been shown to interfere with redox-mediated signaling of cell death. We hypothesized that...

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Pubblicato in:Redox Biol
Autori principali: Crowe, Megan E., Lieven, Christopher J., Thompson, Alex F., Sheibani, Nader, Levin, Leonard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513185/
https://ncbi.nlm.nih.gov/pubmed/26188467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.06.015
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